<b>Ascending pain-related pathways to the anterior cingulate cortex: retrograde transneuronal tracing with rabies virus </b>
نویسندگان
چکیده
منابع مشابه
Organization of multisynaptic inputs from prefrontal cortex to primary motor cortex as revealed by retrograde transneuronal transport of rabies virus.
The organization of multisynaptic projections from the prefrontal cortex to the primary motor cortex (MI) was examined in macaque monkeys by retrograde transneuronal transport of rabies virus. In the first series of experiments, the virus was injected into the MI forelimb region, and the time-dependent distribution patterns of transsynaptic labeling were analyzed in the frontal lobe with variou...
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The neural network that contributes to the suffering which accompanies persistent pain states involves a number of brain regions. Of primary interest is the contribution of the cingulate cortex in processing the affective component of pain. The purpose of this review is to summarize recent data obtained using novel behavioral paradigms in animals based on measuring escape and/or avoidance of a ...
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The rostral anterior cingulate cortex (rACC) is a key structure of pain affect. Whether and how estrogen in the rACC regulates pain-related negative emotion remains unclear. Behaviorally, using formalin-induced conditioned place aversion (F-CPA) in rats, which is believed to reflect the pain-related negative emotion, we found that estrogen receptor (ER) inhibitor ICI 182, 780 (ICI, 7α,17β-[9-[(...
متن کاملCaveats in Transneuronal Tracing with Unmodified Rabies Virus: An Evaluation of Aberrant Results Using a Nearly Perfect Tracing Technique
Apart from the genetically engineered, modified, strains of rabies virus (RABV), unmodified 'fixed' virus strains of RABV, such as the 'French' subtype of CVS11, are used to examine synaptically connected networks in the brain. This technique has been shown to have all the prerequisite characteristics for ideal tracing as it does not metabolically affect infected neurons within the time span of...
متن کاملTransneuronal tracing with neurotropic viruses reveals network macroarchitecture.
A major challenge in systems neuroscience is to unravel the complex matrix of connections that characterize functional circuits within the central nervous system. Retrograde transneuronal transport of rabies virus has proven to be especially useful for this purpose. Here we provide specific examples in which transneuronal transport of rabies virus has been used to unravel multi-synaptic pathway...
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ژورنال
عنوان ژورنال: PAIN RESEARCH
سال: 2004
ISSN: 0915-8588,2187-4697
DOI: 10.11154/pain.19.85